Pharmacological evaluation of a phytotherapeutic product - CPV (dry extract of Crataegus oxyacantha L., Passiflora incarnata L. and Valeriana officinalis L.) in laboratory animals

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Pharmacological evaluation of a phytotherapeutic product - CPV (dry extract of Crataegus oxyacantha L., Passiflora incarnata L. and Valeriana officinalis L.) in laboratory animals

The aim of the present study was to evaluate the central effects of the phytotherapeutic product-CPV (dry extract of Crataegus oxyacantha, Passiflora incarnata and Valeriana officinalis) in animals models. In order to investigate the psychopharmacological profile of CPV extract, an evaluation toward anxiolytic effect of this extract on the elevated plus-maze (EPM) was carried out. Other effects...

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Pharmacognosy and chemotypes of passionflower (Passiflora incarnata L.).

Passionflower (Passiflora incarnata L.) is used in phytotherapy as a mild sedative and anxiolytic agent. In the literature it is clear this plant shows considerable qualitative and quantitative variability with respect to its content of C-glycosyl flavones, some of which are used as marker compounds for extracts. Analysis of plant material cultivated in Australia revealed two chemically distinc...

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Effect of a medicinal plant (Passiflora incarnata L) on sleep

INTRODUCTION Extracts of the plant Passiflora incarnata L. (Passifloraceae) were administered intraperitoneally in order to test its effects on sleep. METHOD Experiments were carried out on chronically implanted male adult wistar rats to obtain cerebral (EEG), ocular (EOG) and muscular (EMG) activities throughout their states of vigilance. Polygraphic recordings were taken during 9 continuous...

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Evaluation of Acute and Sub-acute Toxicity of Ethanolic Dry Fruit Extract of Crataegus Oxycantha L. in Male Wistar Rats

Crataegus oxycantha popularly known as Hawthorn is widely distributed in northern hemisphere especially in Asia, Europe and parts of America. Howthorn consist of more than 200 species and several parts of the plant is traditionally used in the china and Europe. In India it is widely distributed in the temperate Himalayan regions and the different parts of plant is used for multiple health effec...

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Evaluation of Hepatotoxicity of Aqueous Extract of Valerian (Valeriana Officinalis) in Laboratory Mice

Introduction: Concerns have been raised about the toxic effects of medicinal plants due to their increased consumption. Therefore, the aim of the present study was to investigate the hepatotoxic effects of aqueous extract of valerian in laboratory mice. Methods: After preparation of plant materials and aqueous extract of valerian, concentrations of 10 and 20 mg/kg body weight were administered...

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ژورنال

عنوان ژورنال: Revista Brasileira de Farmacognosia

سال: 2009

ISSN: 0102-695X

DOI: 10.1590/s0102-695x2009000200013